Bactroban → Mupirocin Calcium

HRID 16668

反応式

HRID 16668 の反応式
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参加物

3

反応物 1

HCID 6435927Bactroban2 回

生成物 1

HCID 5282317Mupirocin Calcium

試薬・触媒・溶媒 1

HCID 962Water溶媒

反応条件

温度
5 °C

実験手順

Amorphous mupirocin calcium (20.00 g, 19.20 mmole) was added into water (20 ml) under stirring. The slurry was stirred for 0.5 hour, and then it was cooled to 5° C. The mupirocin calcium solution was allowed to crystallize for 16 h. The crystal slurry was diluted with 15 ml water, and the crystals were filtered and washed with water (5 ml). The product (17.1 g) was dried at 35° C. for 12 h.

後処理

  1. stirringThe slurry was stirred for 0.5 hour
  2. customto crystallize for 16 h
  3. additionThe crystal slurry was diluted with 15 ml water
  4. filtrationthe crystals were filtered
  5. washwashed with water (5 ml)
  6. dry with materialThe product (17.1 g) was dried at 35° C. for 12 h.

出典と根拠

ORDレコード
ord-c603df2915db4aa49e683e2e9f3cc60b
出典データセット
uspto-grants-2010_06
特許番号
US07737177B2

関連ノート

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