Dimethylformamide → 2-(6-Bromo-isoquinolin-1-yl carbamoyl)-pyrrolidine-1-carboxylic acid tert-butyl ester

HRID 166719

反応式

[Br:1][c:2]1[cH:3][c:4]2[cH:5][cH:6][n:7][c:8]([NH2:12])[c:9]2[cH:10][cH:11]1.[C:13](=[O:14])([O:15][C:16]([CH3:17])([CH3:18])[CH3:19])[N:20]1[CH:21]([C:22](=[O:23])[OH:24])[CH2:25][CH2:26][CH2:27]1.[CH3:28][N:29]1[CH2:30][CH2:31][O:32][CH2:33][CH2:34]1.[O:59]=[CH:60][N:61]([CH3:62])[CH3:63].[P-:35]([F:36])([F:37])([F:38])([F:39])([F:40])[F:41].[n:42]1([O:43][C:44]([N:45]([CH3:46])[CH3:47])=[N+:48]([CH3:49])[CH3:50])[c:51]2[n:52][cH:53][cH:54][cH:55][c:56]2[n:57][n:58]1>>[Br:1][c:2]1[cH:3][c:4]2[cH:5][cH:6][n:7][c:8]([NH:12][C:22]([CH:21]3[N:20]([C:13](=[O:14])[O:15][C:16]([CH3:17])([CH3:18])[CH3:19])[CH2:27][CH2:26][CH2:25]3)=[O:23])[c:9]2[cH:10][cH:11]1