Ethanol → HCID 178481214、化合物

HRID 1668273ノート

反応式

HRID 1668273 の反応式
[C:1]1([S:7]([C:10]2[CH:15]=[CH:14][C:13]([N:16]3[C:20]4[CH:21]=[CH:22][CH:23]=[CH:24][C:19]=4[N:18]=[CH:17]3)=[CH:12][CH:11]=2)(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[F:25][B-:26]([F:29])([F:28])[F:27].[CH3:30][O+](C)C.C(O)C>ClCCl>[F:25][B-:26]([F:29])([F:28])[F:27].[C:1]1([S:7]([C:10]2[CH:11]=[CH:12][C:13]([N+:16]3[C:20]4[CH:21]=[CH:22][CH:23]=[CH:24][C:19]=4[N:18]([CH3:30])[CH:17]=3)=[CH:14][CH:15]=2)(=[O:9])=[O:8])[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

参加物

5

反応物 3

HCID 702EthanolHCID 2735153Oxonium, trimethyl-, tetrafluoroborate(1-) (1:1)HCID 668793591-(4'-Phenylsulfonylphenyl)benzimidazole

生成物 1

HCID 178481214HCID 178481214、化合物収率 80%

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

A solution of 1-(4′-phenylsulfonylphenyl)benzimidazole (6.7 g, 20 mmol) in dichloromethane (100 ml) is admixed at −10° C. with trimethyloxonium tetrafluoroborate (3.3 g, 22 mmol) and stirred under argon for 16 h. After adding ethanol, the precipitate which forms is filtered off and washed with cold petroleum ether. Yield: 80%.

後処理

  1. filtrationthe precipitate which forms is filtered off
  2. washwashed with cold petroleum ether

出典と根拠

ORDレコード
ord-f73855ed2b2f431fbfae61338204e495
出典データセット
uspto-grants-2011_08
特許番号
US07989091B2

反応ノート

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