3-acetyl-7-nitro-2,3,4,5-tetrahydro-1H-benzo[d]azepine → HCID 21822924、化合物
反応式
[N+:1]([C:4]1[CH:17]=[CH:16][C:7]2[CH2:8][CH2:9][N:10]([C:13](=[O:15])[CH3:14])[CH2:11][CH2:12][C:6]=2[CH:5]=1)([O-])=O>C(O)C>[NH2:1][C:4]1[CH:17]=[CH:16][C:7]2[CH2:8][CH2:9][N:10]([C:13](=[O:15])[CH3:14])[CH2:11][CH2:12][C:6]=2[CH:5]=1参加物
3
実験手順
To a solution of 1-(7-nitro-1,2,4,5-tetrahydrobenzo[d]azepin-3-yl)ethanone (4.0 g) in ethanol (120 ml) 10% Pd/C was added (150 mg) and the mixture hydrogenated for 1 h under a pressure of 30 psi of H2. The mixture was filtered through a celite pad and concentrated to afford a white solid (3.15 g, 90% yield).
後処理
- filtrationThe mixture was filtered through a celite pad
- concentrationconcentrated
出典と根拠
- ORDレコード
- ord-d442dd9c40d54316bd6589f67b6fd415
- 出典データセット
- uspto-grants-2011_08
- 特許番号
- US07989444B2
反応ノート
読み込み中…