Iodine → 2-Bromo-8-iododibenzofuran
反応式
[Br:1][C:2]1[CH:14]=[CH:13][C:5]2[O:6][C:7]3[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=3[C:4]=2[CH:3]=1.[I:15](O)(O)(O)(O)(O)=O.II.S(=O)(=O)(O)O>O.C(O)(=O)C>[Br:1][C:2]1[CH:14]=[CH:13][C:5]2[O:6][C:7]3[CH:12]=[CH:11][C:10]([I:15])=[CH:9][C:8]=3[C:4]=2[CH:3]=1参加物
7
反応条件
- 温度
- 70 °C
実験手順
2-Bromodibenzofuran (2.5 g, 10.1 mmol), orthoperiodic acid (0.49 g, 2.15 mmol), iodine (1.02 g, 4.02 mmol), sulfuric acid, H2O (2 ml) and acetic acid (10 ml) are put into a reaction vessel and the mixture is stirred at 70° C. for 3 hours. After cooling to room temperature the reaction mixture is poured into water and filtered. The white solid is washed by methanol and the desired product is obtained (1.92 g, 51%).
後処理
- temperatureAfter cooling to room temperature the reaction mixture
- filtrationfiltered
- washThe white solid is washed by methanol
出典と根拠
- ORDレコード
- ord-9852295a50264bfe8ffa77266eda349a
- 出典データセット
- uspto-grants-2011_08
- 特許番号
- US07989644B2
反応ノート
読み込み中…