Dicyclohexylcarbodiimide → Sulfo-n-hydroxysulfosuccinimide

HRID 1672117ノート

反応式

HRID 1672117 の反応式
N1(CCCCCCCCCCC(O)=O)C=CC=C1.[OH:19][N:20]1[C:24](=[O:25])[CH2:23][CH:22]([S:26]([OH:29])(=[O:28])=[O:27])[C:21]1=[O:30].C1(N=C=NC2CCCCC2)CCCCC1>CN(C)C=O>[S:26]([C:22]1([S:26]([OH:29])(=[O:28])=[O:27])[CH2:23][C:24](=[O:25])[N:20]([OH:19])[C:21]1=[O:30])([OH:29])(=[O:27])=[O:28]

参加物

5

反応物 3

HCID 10868DicyclohexylcarbodiimideHCID 133909N-HydroxysulfosuccinimideHCID 6734957411-Pyrrol-1-yl-undecanoic acid

生成物 1

HCID 11254355Sulfo-n-hydroxysulfosuccinimide

試薬・触媒・溶媒 1

HCID 6228Dimethylformamide溶媒

実験手順

The following are introduced into a 25 ml round-bottomed flask, in order: 11-(1-pyrrolyl)undecan-1-oic acid (2 mmol; 503 mg), of N-hydroxysulphosuccinimide (2 mmol; 434 mg) and dicyclohexylcarbodiimide (DCC) (2.4 mmol; 495 mg). 10 ml of dimethylformamide (DMF) are subsequently added. A cloudy mixture is obtained, which is subjected to magnetic stirring overnight.

後処理

  1. additionThe following are introduced into a 25 ml round-bottomed flask, in order
  2. customA cloudy mixture is obtained

出典と根拠

ORDレコード
ord-a380c7e186dc4840827cf64bcae7c453
出典データセット
uspto-grants-2011_08
特許番号
US07998726B2

反応ノート

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