Hydrochloric Acid → 2-[2-(2-Fluoro-ethyl)-2H-tetrazol-5-yl]-ethylamine hydrochloride
反応式
C(OC(=O)[NH:7][CH2:8][CH2:9][C:10]1[N:11]=[N:12][N:13]([CH2:15][CH2:16][F:17])[N:14]=1)(C)(C)C.[ClH:19]>ClCCl.O1CCOCC1>[ClH:19].[F:17][CH2:16][CH2:15][N:13]1[N:12]=[N:11][C:10]([CH2:9][CH2:8][NH2:7])=[N:14]1参加物
5
実験手順
A solution of {2-[2-(2-Fluoro-ethyl)-2H-tetrazol-5-yl]-ethyl}-carbamic acid tert-butyl ester (1.0 g, 3.9 mmol) in dichloromethane (30 ml) was treated with a solution of 4M HCl in dioxane (31 ml) and the reaction mixture stirred for 1 hour. The solvent was evaporated to yield the titled product as a white solid.
後処理
- customThe solvent was evaporated
出典と根拠
- ORDレコード
- ord-ace71a3ec12044b3a6a2ec2fe92a4de4
- 出典データセット
- uspto-grants-2011_08
- 特許番号
- US07998990B2
反応ノート
読み込み中…