4,6-Dichloro-2-(methylthio)pyrimidine → HCID 66991899、化合物

反応式

Cl[C:2]1[CH:7]=[C:6](Cl)[N:5]=[C:4]([S:9][CH3:10])[N:3]=1.[CH2:11]([NH:13][C:14]1[CH:15]=[C:16]([OH:20])[CH:17]=[CH:18][CH:19]=1)[CH3:12]>>[CH3:10][S:9][C:4]1[N:5]=[C:6]([N:13]([CH2:11][CH3:12])[C:14]2[CH:19]=[CH:18][CH:17]=[C:16]([OH:20])[CH:15]=2)[CH:7]=[C:2]([N:13]([CH2:11][CH3:12])[C:14]2[CH:19]=[CH:18][CH:17]=[C:16]([OH:20])[CH:15]=2)[N:3]=1

参加物

反応物 2

HCID 805314,6-Dichloro-2-(methylthio)pyrimidine

HCID 5789913-Ethylaminophenol

生成物 1

HCID 66991899HCID 66991899、化合物収率 43%

実験手順

This compound was obtained (yield 43%) based on the method described in Production Example 2B using 4,6-dichloro-2-methylthio-pyrimidine instead of the 4,6-dichloro-2-ethylpyrimidine, and using 3-ethylaminophenol instead of the 3-aminophenol.

後処理

customThis compound was obtained (yield 43%)

出典と根拠

ORDレコード: ord-72aaebd6dd38411091691b2fdee932fe
出典データセット: uspto-grants-2011_08
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08003645B2

反応ノート

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