4-Fluoroanisole → 5-Fluoro-2-methoxybenzene-1-sulfonyl chloride

関与物質

反応手順

4-Fluoroanisole (10.0 g) was carefully added to chlorosulphonic acid (45.81 g) at 0° C. The mixture was stirred at RT for 2 h, then quenched with ice-water (500 ml) and the solid filtered and dried, yield 16.50 g.

情報源と証拠