化工社化工社 化学情報印刷レポート · 研究参考用
1-(Cyclopropylmethyl)piperazine → N-[2-(4-Chloro-phenyl)-ethyl]-6-(4-cyclopropylmethyl-piperazin-1-yl)-nicotinamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-(Cyclopropylmethyl)piperazine | HCID 965875 | — |
| 反応物 | 6-chloro-N-[2-(4-chlorophenyl)ethyl]pyridine-3-carboxamide | HCID 8088154 | — |
| 生成物 | N-[2-(4-Chloro-phenyl)-ethyl]-6-(4-cyclopropylmethyl-piperazin-1-yl)-nicotinamide | HCID 57571679 | — |
反応手順
In analogy to example 1.a 6-chloro-N-[2-(4-chloro-phenyl)-ethyl]-nicotinamide was reacted with 1-(cyclopropylmethyl)piperazine. Off-white solid. MS (ISP): 399.3 ([M+H]+)
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08008305B2 |
| 出典データセット | uspto-grants-2011_08 |
| ORD ID | ord-bae1e122d12f4746904210ca1a24a93d |
| 出典メモ | uspto-grants-2011_08 |