戻る
化工社化工社 化学情報印刷レポート · 研究参考用
HRID 1677180作成日：2026年10月27日

(4-(Methylsulfinyl)phenyl)boronic acid → (3-Fluoro-4'-methanesulfinyl-biphenyl-4-yl)-(2-(S)-pyrrolidin-1-ylmethyl-pyrrolidin-1-yl)-methanone

https://huagongshe.com/reaction/1677180

反応式

関与物質

役割名称HCID仕込み量
反応物(4-(Methylsulfinyl)phenyl)boronic acidHCID 2773531—
反応物(4-Bromo-2-fluoro-phenyl)-((S)-2-pyrrolidin-1-ylmethyl-pyrrolidin-1-yl)-methanoneHCID 11965125—
生成物(3-Fluoro-4'-methanesulfinyl-biphenyl-4-yl)-(2-(S)-pyrrolidin-1-ylmethyl-pyrrolidin-1-yl)-methanoneHCID 57980145—

反応手順

The title compound is prepared in a manner substantially analogous to Procedure SS starting from (4-bromo-2-fluoro-phenyl)-(2-(S)-pyrrolidin-1-ylmethyl-pyrrolidin-1-yl)-methanone and 4-Methylsulfinyl benzene boronic acid. MS (M+H) 415.1

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US08008301B2
出典データセットuspto-grants-2011_08
ORD IDord-bc3b3e16165c46a1b2c377a0a916168e
出典メモuspto-grants-2011_08