戻る
化工社化工社 化学情報印刷レポート · 研究参考用
HRID 1677475作成日：2026年10月26日

N-methyl-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)aniline → [2-(4-Methylamino-phenyl)-5H-pyrrolo[2,3-b]pyrazin-7-yl]-(1-methyl-cyclohexyl)-methanone

https://huagongshe.com/reaction/1677475

反応式

関与物質

役割名称HCID仕込み量
反応物N-methyl-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)anilineHCID 11957892—
反応物(2-bromo-5H-pyrrolo[2,3-b]pyrazin-7-yl)-(1-methyl-cyclohexyl)-methanoneHCID 44199730—
生成物[2-(4-Methylamino-phenyl)-5H-pyrrolo[2,3-b]pyrazin-7-yl]-(1-methyl-cyclohexyl)-methanoneHCID 59540838—

反応手順

[2-(4-Methylamino-phenyl)-5H-pyrrolo[2,3-b]pyrazin-7-yl]-(1-methyl-cyclohexyl)-methanone was prepared starting from (2-bromo-5H-pyrrolo[2,3-b]pyrazin-7-yl)-(1-methyl-cyclohexyl)-methanone and methyl-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-amine following general procedures as described in these Examples. MP 273-275° C., M+H=349.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US08008298B2
出典データセットuspto-grants-2011_08
ORD IDord-0634f7bd39f345fe8fe8c42bc1edad90
出典メモuspto-grants-2011_08