Ethanol → HCID 86735514、化合物

反応式

[NH:1]([C:3]1[N:7]([CH3:8])[N:6]=[C:5]([CH3:9])[C:4]=1[N+:10]([O-:12])=[O:11])[NH2:2].[CH2:13]([O:15][C:16](=[O:27])[C:17](=[CH:23]OCC)[C:18]([C:20]([OH:22])=[O:21])=O)[CH3:14].[CH2:28](O)[CH3:29]>>[CH3:8][N:7]1[C:3]([N:1]2[C:18]([C:20]([O:22][CH2:28][CH3:29])=[O:21])=[C:17]([C:16]([O:15][CH2:13][CH3:14])=[O:27])[CH:23]=[N:2]2)=[C:4]([N+:10]([O-:12])=[O:11])[C:5]([CH3:9])=[N:6]1

参加物

反応物 3

HCID 702Ethanol2 回

HCID 35372575-Hydrazino-1,3-dimethyl-4-nitro-1H-pyrazole

HCID 54255144Ethoxymethylene oxalacetic acid ethyl ester

生成物 1

HCID 86735514HCID 86735514、化合物

実験手順

120 gms. of 5-hydrazino-1,3-dimethyl-4-nitro-1H-pyrazole are dissolved in 500 ml. of absolute ethanol and 173 gms. of ethoxymethylene oxalacetic acid ethyl ester dissolved in 300 ml. of ethanol are slowly added dropwise. After refluxing for 10 hours and distilling off the solvent, the product, 1-(1,3-dimethyl-4-nitro-1H-pyrazol-5-yl)-1H-pyrazole-4,5-dicarboxylic acid, diethyl ester, is obtained as a brown oil, which crystallizes on trituration with cold ether, yield 143 gms. after recrystallization from cyclohexane/benzene, yellow crystals, m.p. 70°-80°.