Potassium Hydroxide → 3-Cyano-4-carbamoyl-1,2,5-thiadiazole

HRID 1678867ノート

反応式

HRID 1678867 の反応式
[C:1]([C:3]1[C:7]([C:8]#[N:9])=[N:6][S:5][N:4]=1)#[N:2].[OH-:10].[K+]>O>[C:1]([C:3]1[C:7]([C:8](=[O:10])[NH2:9])=[N:6][S:5][N:4]=1)#[N:2]

参加物

4

反応物 2

HCID 14797Potassium HydroxideHCID 38252271,2,5-Thiadiazole-3,4-dicarbonitrile2 回

生成物 1

HCID 203646513-Cyano-4-carbamoyl-1,2,5-thiadiazole

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

First, one mole of solid 3,4-dicyano-1,2,5-thiadiazole (II) is suspended in a quantity of water sufficient to obtain an easily stirrable mixture. Then, under stirring, there are admixed from 0.01 to 0.8 mole of KOH in the form of an aqueous solution. There occurs an exothermic reaction which is controlled by cooling so as to maintain a temperature of about 20° to 50° C. At this stage the 3,4-dicyano-1,2,5-thiadizole (II) passes into solution, hydrating to form 3-cyano-4-carbamoyl-1,2,5-thiadiazole (III), which may be separated as a solid if one operates at 20° to 35° C, or which will remain in solution if one operates at higher temperatures up to 50° C. This ends the first stage of the reaction.

後処理

  1. customto obtain an easily stirrable mixture
  2. customan exothermic reaction which
  3. temperatureby cooling so as
  4. temperatureto maintain a temperature of about 20° to 50° C

出典と根拠

ORDレコード
ord-83997409c58e476d8c55dafd6f708e66
出典データセット
uspto-grants-1978_03
特許番号
US04077966

反応ノート

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