Water → 2,3,4,9-Tetrahydro-6-methoxy-1H-carbazol-1-one

HRID 1679824ノート

反応式

HRID 1679824 の反応式
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([NH:9]N=C2CCCCC2=O)=[CH:5][CH:4]=1.[OH2:18].S(=O)(=O)(O)O>C(O)C>[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:6](=[CH:7][CH:8]=1)[NH:9][C:4]1[C:5](=[O:18])[CH2:6][CH2:7][CH2:8][C:3]2=1

参加物

5

反応物 3

HCID 962WaterHCID 1118Sulfuric AcidHCID 753926HCID 753926、化合物

生成物 1

HCID 28568112,3,4,9-Tetrahydro-6-methoxy-1H-carbazol-1-one

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

232 g. (1 mole) of cyclohexanedione-mono-p-methoxyphenylhydrazone, 1200 ml. of water, 350 g. of sulfuric acid (65 Be) and 100 ml. of ethanol are allowed to boil under reflux for three hours. After cooling down, the mixture is filtered with suction and rendered free from acid by washing with water. The resultant 6-methoxy-1,2,3,4-tetrahydrocarbazol-1-one melts at 222° C. and gives a yield of 193 g. (=90% of the theoretical).

後処理

  1. temperatureunder reflux for three hours
  2. temperatureAfter cooling down
  3. filtrationthe mixture is filtered with suction
  4. washby washing with water

出典と根拠

ORDレコード
ord-c8c3d8b5a40a47e1b2c19341d86dfc4c
出典データセット
uspto-grants-1981_06
特許番号
US04271073

反応ノート

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