Water → Eltenac

HRID 1680167ノート

反応式

HRID 1680167 の反応式
[Cl:1][C:2]1[CH:17]=[CH:16][CH:15]=[C:14]([Cl:18])[C:3]=1[NH:4][C:5]1[C:6]([CH2:10][C:11](N)=[O:12])=[CH:7][S:8][CH:9]=1.[OH2:19]>S(=O)(=O)(O)O>[Cl:1][C:2]1[CH:17]=[CH:16][CH:15]=[C:14]([Cl:18])[C:3]=1[NH:4][C:5]1[C:6]([CH2:10][C:11]([OH:19])=[O:12])=[CH:7][S:8][CH:9]=1

参加物

4

反応物 2

HCID 962WaterHCID 23457236HCID 23457236、化合物

生成物 1

HCID 51717Eltenac

試薬・触媒・溶媒 1

HCID 1118Sulfuric Acid溶媒

実験手順

30.1 g (0.1 mole) of 4-(2,6-dichloroanilino)-3-thiophenacetamide are warmed to 100° in 135 ml of concentrated sulfuric acid and 49 ml of water for 3 hours. The mixture is poured onto ice, and the precipitate of 4-(2,6-dichloroanilino)-3-thiophenacetic acid which has formed in filtered off. The precipitate is boiled up with diisopropyl ether and dried; it then melts at 179° to 180°.

後処理

  1. additionThe mixture is poured onto ice

出典と根拠

ORDレコード
ord-14cf263212bc43c69a5aa83dcd34dc40
出典データセット
uspto-grants-1981_06
特許番号
US04272507

反応ノート

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