Sulfuric Acid → HCID 23457236、化合物

HRID 1680168ノート

反応式

HRID 1680168 の反応式
[Cl:1][C:2]1[CH:16]=[CH:15][CH:14]=[C:13]([Cl:17])[C:3]=1[NH:4][C:5]1[C:6]([CH2:10][C:11]#[N:12])=[CH:7][S:8][CH:9]=1.S(=O)(=O)(O)[OH:19]>>[Cl:1][C:2]1[CH:16]=[CH:15][CH:14]=[C:13]([Cl:17])[C:3]=1[NH:4][C:5]1[C:6]([CH2:10][C:11]([NH2:12])=[O:19])=[CH:7][S:8][CH:9]=1

参加物

3

反応物 2

HCID 1118Sulfuric AcidHCID 23457191HCID 23457191、化合物

生成物 1

HCID 23457236HCID 23457236、化合物

実験手順

28.3 g (0.1 mole) of 4-(2,6-dichloroanilino)-3-thiophenacetonitrile are introduced into 150 ml of concentrated sulfuric acid and stirred for one hour at room temperature. It is poured onto ice, and the precipitate which has formed is filtered off. Recrystallization from ethyl acetate yields 4-(2,6-dichloroanilino)-3-thiophenacetamide (m. 172° to 173°).

後処理

  1. additionIt is poured onto ice
  2. customthe precipitate which has formed
  3. filtrationis filtered off
  4. customRecrystallization from ethyl acetate

出典と根拠

ORDレコード
ord-b9379a39fe8b4647abdcb1855130d5cb
出典データセット
uspto-grants-1981_06
特許番号
US04272507

反応ノート

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