2-Methoxyethanol → Ethanamine, 2-(2-methoxyethoxy)-N,N-bis[2-(2-methoxyethoxy)ethyl]-

HRID 1680521ノート

反応式

HRID 1680521 の反応式
Cl.Cl[CH2:3][CH2:4][N:5]([CH2:9][CH2:10]Cl)[CH2:6][CH2:7]Cl.[CH3:12][O:13][CH2:14][CH2:15][OH:16]>>[CH2:4]([N:5]([CH2:9][CH2:10][O:16][CH2:15][CH2:14][O:13][CH3:12])[CH2:6][CH2:7][O:16][CH2:15][CH2:14][O:13][CH3:12])[CH2:3][O:16][CH2:15][CH2:14][O:13][CH3:12]

参加物

3

反応物 2

HCID 80192-MethoxyethanolHCID 61220Tris(2-chloroethyl)amine hydrochloride

生成物 1

HCID 112414Ethanamine, 2-(2-methoxyethoxy)-N,N-bis[2-(2-methoxyethoxy)ethyl]-

実験手順

To the preceding mixture, 51.6 g tris-(2-chloroethyl)amine hydrochloride (0.215 mole) were added. The mixture was then heated under reflux of the 2-methoxyethanol (θ=125° C.) for 12 hours and the solvent distilled off under reduced pressure. The excess sodium 2-methoxyethanolate was neutralized by addition of 11.6 cm3 of aqueous (10 N) HCl. The sodium chloride was filtered and the solution distilled.

後処理

  1. temperatureThe mixture was then heated
  2. distillationthe solvent distilled off under reduced pressure
  3. additionThe excess sodium 2-methoxyethanolate was neutralized by addition of 11.6 cm3 of aqueous (10 N) HCl
  4. filtrationThe sodium chloride was filtered
  5. distillationthe solution distilled

出典と根拠

ORDレコード
ord-562d5e4fb5c145b2b0f8736c0f8d05d9
出典データセット
uspto-grants-1981_06
特許番号
US04273915

反応ノート

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