Diethyl Ether → HCID 178444538、化合物

HRID 1680557ノート

反応式

HRID 1680557 の反応式
[Cr](Cl)([O-])(=O)=O.[NH+]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1.C(Cl)Cl.CC[O:17][CH2:18][CH3:19]>>[CH2:7]([C@H:9]1[CH2:10][CH2:11][C@H:19]([CH:18]=[O:17])[CH2:7][CH2:8]1)[CH2:8][CH2:9][CH2:10][CH3:11]

参加物

4

反応物 3

HCID 3283Diethyl Ether2 回HCID 6344DichloromethaneHCID 178418287HCID 178418287、化合物

生成物 1

HCID 178444538HCID 178444538、化合物

実験手順

A solution of 59.0 g. of trans-4-n-pentylcyclohexane carbinol in 100 ml. of ether is added to a suspension of 125 g. of pyridinium chlorochromate in 900 ml. of methylene chloride and the mixture is stirred at room temperature for 2 hours. The mixture is then diluted with 400 ml. of ether, stirred for a further 15 minutes and the solution is decanted off from the tarry precipitate. The precipitate is back-washed with ether. The combined organic solutions are filtered through a Florisil column. The trans-4-n-pentylcyclohexane carboxaldehyde obtained after evaporation of the filtrate is used directly in the next step.

後処理

  1. additionThe mixture is then diluted with 400 ml
  2. customthe solution is decanted off from the tarry precipitate
  3. washThe precipitate is back-washed with ether
  4. filtrationThe combined organic solutions are filtered through a Florisil column

出典と根拠

ORDレコード
ord-c11b8a1508b64791b4dbb577ba4945fe
出典データセット
uspto-grants-1981_06
特許番号
US04273929

反応ノート

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