化工社化工社 化学情報印刷レポート · 研究参考用
Chloroacetyl chloride → 2-Chloro-1-(2,3,5,6-tetramethylphenyl)ethanone
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Chloroacetyl chloride | HCID 6577 | — |
| 反応物 | Durene | HCID 7269 | — |
| 反応物 | Aluminum(III) Chloride | HCID 6451240 | — |
| 生成物 | 2-Chloro-1-(2,3,5,6-tetramethylphenyl)ethanone | HCID 2497447 | 84.6% |
反応手順
Example 1 was repeated but 1.33 g of aluminium trichloride, 1.13 g of chloroacetyl chloride and 1.34 g of durene were employed. 1.78 g of 3-chloroacetyl-durene were obtained, melting point 65.5°=66° C. The product was purified by distillation (bp 113°-117° C.)/0.4 mmHg) and crystallized from ethanol. Similarly, 3-bromoacetyl-durene, melting 53°-54° C. was obtained.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04275071 |
| 出典データセット | uspto-grants-1981_06 |
| ORD ID | ord-3fc0a73a53984d14841e33a9b0a4e689 |
| 出典メモ | uspto-grants-1981_06 |