関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Styrene Oxide | HCID 7276 | — |
| 反応物 | 2-(Benzyloxy)propan-1-amine | HCID 296015 | — |
| 生成物 | alpha-[[[2-(Phenylmethoxy)propyl]amino]methyl]benzenemethanol | HCID 19806395 | 84.1% |
反応手順
A mixture of styrene oxide (1.96 g, 0.010 mol) and 2-benzyloxypropylamine (2.48 g, 0.15 mol) was heated at 140° C. for 6 hours and then allowed to cool to ambient temperature and stand for 12 hours. The solidified reaction mixture was triturated with isooctane and filtered to obtain an impure solid that was recrystallized from isooctane to obtain 2.40 g of a white solid (84% yield); mp 90°-100° C. (undefined).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US05171753 |
|---|
| 出典データセット | uspto-grants-1992_12 |
|---|
| ORD ID | ord-9930972b977f40ce97126d92214321de |
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| 出典メモ | uspto-grants-1992_12 |
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