Hydrochloric Acid → HCID 21612964、化合物
反応式
[NH2:1][CH:2](/[CH:6]=[CH:7]/[CH2:8][P:9]([OH:12])([OH:11])=[O:10])[C:3]([OH:5])=[O:4].Cl.[CH2:14](O)[CH:15]([CH3:17])[CH3:16]>>[CH2:14]([O:4][C:3](=[O:5])[CH:2]([NH2:1])/[CH:6]=[CH:7]/[CH2:8][P:9]([OH:12])([OH:11])=[O:10])[CH:15]([CH3:17])[CH3:16]参加物
4
実験手順
1.5 g of E-2-amino-5-phosphono-3-pentenoic acid are suspended in 30 ml of isobutanol and the suspension is saturated with hydrogen chloride gas for 31/2 hours at 70°. After concentration, the residue is dissolved in 10 ml of isobutanol, 10 ml of propylene oxide are added and the precipitate is filtered off. Recrystallisation from water/acetone 1:1 yields E-2-amino-5-phosphono-3-pentenoic acid isobutyl ester, m.p. 163°-164°.
後処理
- custom2 hours
- customat 70°
- concentrationAfter concentration
- dissolutionthe residue is dissolved in 10 ml of isobutanol
- addition10 ml of propylene oxide are added
- filtrationthe precipitate is filtered off
- customRecrystallisation from water/acetone 1:1
出典と根拠
- ORDレコード
- ord-d6233a39d199498884d55f8945913e01
- 出典データセット
- uspto-grants-1992_12
- 特許番号
- US05175344
反応ノート
読み込み中…