Sodium Methoxide → N-benzoyl-3-methoxycaprolactam
反応式
ClC1CCCNC(=O)C1.C[O-].[Na+].[C:13]([N:21]1[CH2:26][CH2:25]O[CH2:23][C:22]1=[O:27])(=[O:20])[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1.[CH3:28][O:29][CH:30]1[CH2:37][CH2:36][CH2:35][NH:34][C:32](=[O:33])[CH2:31]1>>[CH3:28][O:29][CH:30]1[CH2:37][CH2:36][CH2:35][NH:34][C:32](=[O:33])[CH2:31]1.[C:13]([N:21]1[CH2:26][CH2:25][CH2:31][CH:30]([O:29][CH3:28])[CH2:23][C:22]1=[O:27])(=[O:20])[C:14]1[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=1参加物
6
実験手順
3-Methoxycaprolactam was prepared from 3-chlorocaprolactam (prepared as described in Francis, et al. J. Am. Chem. Soc. 1958, 80, 6238) and sodium methoxide according to the method of Kondelikova, et al. (Collect. Czech. Chem. Commun. 1971, 36(9), 3391). The desired product N-benzoyl-3-methoxycaprolactam is synthesized as for N-benzoyl-3-oxomorpholine (Example I) using 3 -methoxycaprolactam in place of morpholin-3-one.
出典と根拠
- ORDレコード
- ord-9aa69dbbb2814954beb15485a083d590
- 出典データセット
- uspto-grants-1997_06
- 特許番号
- US05635103
反応ノート
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