Ammonium → 2-Carbamoyl-3-nitrobenzoic acid

HRID 1682559

反応式

HRID 1682559 の反応式
[N+:1]([C:4]1[CH:14]=[CH:13][CH:12]=[C:6]2[C:7]([O:9][C:10](=[O:11])[C:5]=12)=[O:8])([O-:3])=[O:2].[NH4+:15]>>[C:7]([C:6]1[CH:12]=[CH:13][CH:14]=[C:4]([N+:1]([O-:3])=[O:2])[C:5]=1[C:10]([NH2:15])=[O:11])([OH:9])=[O:8]

参加物

3

反応物 2

HCID 223AmmoniumHCID 216313-Nitrophthalic anhydride

生成物 1

HCID 4375472-Carbamoyl-3-nitrobenzoic acid

反応条件

温度
100 °C

実験手順

30 g (0.155 mol) of 3-nitrophthalic anhydride are introduced in portions into 180 ml of conc. ammonium solution and the resulting solution is heated at 100° C. with stirring for 45 min. The mixture is evaporated in a rotary evaporator and co-distilled twice with toluene, and the residue is dried in a high vacuum. It is stirred with EA, and the beige precipitate is filtered off with suction and dried in vacuo over P2O5. 31.8 g of the title compound are obtained.

後処理

  1. customThe mixture is evaporated in a rotary evaporator
  2. customthe residue is dried in a high vacuum
  3. stirringIt is stirred with EA
  4. filtrationthe beige precipitate is filtered off with suction
  5. dry with materialdried in vacuo over P2O5

出典と根拠

ORDレコード
ord-df4b8d0cef924049a7fb793f17b8495a
出典データセット
uspto-grants-1997_06
特許番号
US05635525

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