Boron tribromide → HCID 19040965、化合物
反応式
C[O:2][C:3]1[CH:17]=[C:16]([O:18]C)[CH:15]=[CH:14][C:4]=1[C:5]([N:7]([CH:11]([CH3:13])[CH3:12])[CH:8]([CH3:10])[CH3:9])=[O:6].B(Br)(Br)Br>ClCCl>[OH:2][C:3]1[CH:17]=[C:16]([OH:18])[CH:15]=[CH:14][C:4]=1[C:5]([N:7]([CH:11]([CH3:12])[CH3:13])[CH:8]([CH3:9])[CH3:10])=[O:6]参加物
4
実験手順
A solution of 2,4-dimethoxy-N,N-bis(1-methylethyl)benzamide (3.0 g, 11.0 mmol) in 10 ml of dichloromethane at 0° C. is treated with 1N boron tribromide (33.0 mL, 33.0 mmol) and stirred at room temperature for 2 hours. The reaction is concentrated in vacuo, dissolved in 1N sodium hydroxide solution, and acidified with 1N hydrochloric acid to generate solid which is filtered to afford 2,4-dihydroxy-N,N-bis(1-methylethyl)benzamide as white solid.
後処理
- concentrationThe reaction is concentrated in vacuo
- dissolutiondissolved in 1N sodium hydroxide solution
- filtrationis filtered
出典と根拠
- ORDレコード
- ord-38661e6e5c8349afb4df93eb2fbdd7e8
- 出典データセット
- uspto-grants-1997_06
- 特許番号
- US05639768
反応ノート
読み込み中…