2,4-Heptanedione, 6-methyl- → 4-(3,4-Dimethoxyphenyl)-3-isovaleryl-6,7-dimethoxy-2-methylquinoline

HRID 1684577

反応式

HRID 1684577 の反応式
Cl.[NH2:2][C:3]1[CH:20]=[C:19]([O:21][CH3:22])[C:18]([O:23][CH3:24])=[CH:17][C:4]=1[C:5]([C:7]1[CH:12]=[CH:11][C:10]([O:13][CH3:14])=[C:9]([O:15][CH3:16])[CH:8]=1)=O.[CH3:25][CH:26]([CH3:34])[CH2:27][C:28](=[O:33])[CH2:29][C:30](=O)[CH3:31]>>[CH3:16][O:15][C:9]1[CH:8]=[C:7]([C:5]2[C:4]3[C:3](=[CH:20][C:19]([O:21][CH3:22])=[C:18]([O:23][CH3:24])[CH:17]=3)[N:2]=[C:30]([CH3:31])[C:29]=2[C:28](=[O:33])[CH2:27][CH:26]([CH3:34])[CH3:25])[CH:12]=[CH:11][C:10]=1[O:13][CH3:14]

参加物

3

反応物 2

HCID 763542,4-Heptanedione, 6-methyl-HCID 214661342-Amino-3',4',4,5-tetramethoxybenzophenone hydrochloride

生成物 1

HCID 190399034-(3,4-Dimethoxyphenyl)-3-isovaleryl-6,7-dimethoxy-2-methylquinoline

実験手順

According to the same manner as that described in Reference Example 6, 2-amino-3',4',4,5-tetramethoxybenzophenone hydrochloride was reacted with 6-methyl-2,4-heptanedione to give 4-(3,4-dimethoxyphenyl)-3-isovaleryl-6,7-dimethoxy-2-methylquinoline. This compound was recrystallized from ethyl acetate-hexane to give colorless prisms. mp. 135°-137° C.

出典と根拠

ORDレコード
ord-ab1656257a47449eb2535eb25de22302
出典データセット
uspto-grants-1997_06
特許番号
US05641788

関連ノート

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