化工社化工社 化学情報印刷レポート · 研究参考用
Morpholine → 4-[(3-Chloro-4-fluorophenyl)sulfonyl]morpholine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Morpholine | HCID 8083 | — |
| 反応物 | 3-Chloro-4-fluorobenzenesulphonyl chloride | HCID 145222 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | 4-[(3-Chloro-4-fluorophenyl)sulfonyl]morpholine | HCID 697826 | — |
反応手順
4-fluoro-3-chlorobenzenesulphonyl chloride (0.9 g) was stirred in dry DCM (10 ml) and morpholine (0.69 ml) added. The mixture was allowed to stir at RT for 1 h and then quenched with water, extracted with DCM, dried (MgSO4) and evaporated under reduced pressure to give a white solid (1.10 g).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08148572B2 |
| 出典データセット | uspto-grants-2012_04 |
| ORD ID | ord-9630a25f50aa454dade9a9dfd6f7ac7e |
| 出典メモ | uspto-grants-2012_04 |