2-Chloro-1-fluoro-4-[(3-fluorobenzyl)sulfonyl]benzene → [3-{2-Chloro-4-[(3-fluorobenzyl)sulfonyl]phenoxy}-5-(trifluoromethyl)phenyl]acetic acid

HRID 1686449

反応式

HRID 1686449 の反応式
[OH:1][C:2]1[CH:3]=[C:4]([CH2:12][C:13]([OH:15])=[O:14])[CH:5]=[C:6]([C:8]([F:11])([F:10])[F:9])[CH:7]=1.[Cl:16][C:17]1[CH:22]=[C:21]([S:23]([CH2:26][C:27]2[CH:32]=[CH:31][CH:30]=[C:29]([F:33])[CH:28]=2)(=[O:25])=[O:24])[CH:20]=[CH:19][C:18]=1F>>[Cl:16][C:17]1[CH:22]=[C:21]([S:23]([CH2:26][C:27]2[CH:32]=[CH:31][CH:30]=[C:29]([F:33])[CH:28]=2)(=[O:25])=[O:24])[CH:20]=[CH:19][C:18]=1[O:1][C:2]1[CH:3]=[C:4]([CH2:12][C:13]([OH:15])=[O:14])[CH:5]=[C:6]([C:8]([F:9])([F:10])[F:11])[CH:7]=1

参加物

3

反応物 2

HCID 689515022-Chloro-1-fluoro-4-[(3-fluorobenzyl)sulfonyl]benzeneHCID 690656243-Hydroxy-5-(trifluoromethyl)phenylacetic acid

生成物 1

HCID 16123765[3-{2-Chloro-4-[(3-fluorobenzyl)sulfonyl]phenoxy}-5-(trifluoromethyl)phenyl]acetic acid

実験手順

The title compound was prepared as described in example 2 step (iii) but instead using the product from example 25 step (iv) and the product from step (i).

出典と根拠

ORDレコード
ord-98964fa52e994304ba10deb5589c8f76
出典データセット
uspto-grants-2012_04
特許番号
US08148572B2

関連ノート

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