Boron trifluoride etherate → HCID 67281057、化合物
反応式
B(F)(F)F.CCOCC.[F:10][C:11]([F:30])([F:29])[C:12]1[CH:28]=[CH:27][C:15]([O:16][CH2:17][C:18]([O:20][CH2:21][C:22]2([CH3:26])[CH2:25][O:24][CH2:23]2)=[O:19])=[CH:14][CH:13]=1>ClCCl>[CH3:23][C:22]12[CH2:25][O:24][C:18]([CH2:17][O:16][C:15]3[CH:27]=[CH:28][C:12]([C:11]([F:30])([F:29])[F:10])=[CH:13][CH:14]=3)([O:19][CH2:26]1)[O:20][CH2:21]2参加物
4
実験手順
Boron trifluoride diethyl etherate (1.48 ml) was added to a solution of the product from step (ii) (14.2 g) in dichloromethane at −78° C. The cooling bath was removed, the mixture, stirred for 3 h then triethylamine (6.2 ml) added. The mixture was reduced to half the volume under reduced pressure then filtered. The filtrate was evaporated under reduced pressure then the residue purified by chromatography on silica (pre-eluted with one column volume of neat triethylamine) eluting with dichloromethane, yield 11.1 g.