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(2S)-2-[2-borono-4-(trifluoromethyl)phenoxy]-propanoic acid → 2-[[2'-Chloro-4'-[(dimethylamino)sulfonyl]-5-(trifluoromethyl)[1,1'-biphenyl]-2-yl]oxy]-(2S)-propanoic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | (2S)-2-[2-borono-4-(trifluoromethyl)phenoxy]-propanoic acid | HCID 67277101 | — |
| 反応物 | 3-Chloro-4-iodo-N,N-dimethylbenzenesulfonamide | HCID 67280204 | — |
| 生成物 | 2-[[2'-Chloro-4'-[(dimethylamino)sulfonyl]-5-(trifluoromethyl)[1,1'-biphenyl]-2-yl]oxy]-(2S)-propanoic acid | HCID 11476492 | — |
反応手順
The title compound was prepared by the method of example 144 step (i) using the product from step (ii) and the product from example 146 step (iv).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08158820B2 |
| 出典データセット | uspto-grants-2012_04 |
| ORD ID | ord-9dd2adb4d5c140d6955b8e9b625e2da3 |
| 出典メモ | uspto-grants-2012_04 |