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4-Bromo-N,N-dimethylbenzenesulphonamide → [[5-Chloro-4'-[(dimethylamino)sulfonyl][1,1'-biphenyl]-2-yl]oxy]-(2s)-propanoic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-Bromo-N,N-dimethylbenzenesulphonamide | HCID 12818 | — |
| 反応物 | (2S)-2-(2-borono-4-chlorophenoxy)-propanoic acid | HCID 67277298 | — |
| 溶媒 | Tetrahydrofuran | HCID 8028 | — |
| 生成物 | [[5-Chloro-4'-[(dimethylamino)sulfonyl][1,1'-biphenyl]-2-yl]oxy]-(2s)-propanoic acid | HCID 11429045 | — |
反応手順
The title compound was prepared by the method of example 144 step (i) using the product from step (iv) and 4-bromo-N,N-dimethylbenzenesulfonamide and THF as solvent. Yield (0.068 g).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08158820B2 |
| 出典データセット | uspto-grants-2012_04 |
| ORD ID | ord-9b4d93441cba419b8d4b27d060596aed |
| 出典メモ | uspto-grants-2012_04 |