1-Iodohexane → HCID 16110922、化合物

反応式

[C:1]([O:5][C:6](=[O:17])[CH2:7][C@H:8]([OH:16])[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH3:15])([CH3:4])([CH3:3])[CH3:2].I[CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH3:24]>>[C:1]([O:5][C:6](=[O:17])[C@H:7]([CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH3:24])[C@H:8]([OH:16])[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH3:15])([CH3:2])([CH3:4])[CH3:3]

参加物

反応物 2

HCID 125271-Iodohexane

HCID 16110964tert-Butyl (3R)-3-hydroxydecanoate

生成物 1

HCID 16110922HCID 16110922、化合物

実験手順

The target compound (1.80 g, 33%) was obtained in the same manner as in Production Example C-1, except that the (R)-3-hydroxydecanoic acid t-butyl ester (4.00 g, 16.4 mmol) obtained in Production Example B-5 and 1-iodohexane (5.20 g, 24.5 mmol) were used.

出典と根拠

ORDレコード: ord-07042038c00844f3b98640fdb0ad4756
出典データセット: uspto-grants-2012_04
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08163713B2

反応ノート

読み込み中…