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HRID 1695241作成日:2026年10月27日

Formate → HCID 178520650、化合物

https://huagongshe.com/reaction/1695241

反応式

関与物質

役割名称HCID仕込み量
反応物FormateHCID 283—
反応物Butyric acid, 4-piperidino-HCID 20794—
反応物HCID 178507293HCID 178507293—
生成物HCID 178520650HCID 17852065028%

反応手順

The product was prepared according to the general synthetic method for the synthesis of ω-amino-alkanoic acid (1H-pyrazol-3-yl-5-aryl)-amides via the amino acid route, starting from 5-(4-cyclopropylmethoxy-phenyl)-2H-pyrazol-3-ylamine (152.9 mg, 0.7 mmol, 1.0 eq) and 4-piperidin-1-yl-butyric acid (168 mg, 1.0 mmol, 1.5 eq). The crude product was purified via preparative HPLC; 72.0 mg of the title product (28% yield) was obtained as a formate salt.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US08163729B2
出典データセットuspto-grants-2012_04
ORD IDord-72fb51b6e0614cacb579e72814fe1012
出典メモuspto-grants-2012_04