N'-[4-(1,2,2,6,6-Pentamethyl-piperidin-4-ylcarbamoyl)-phenyl]-hydrazinecarboxylic acid tert-butyl ester → 4-Hydrazino-N-(1,2,2,6,6-pentamethyl-piperidin-4-yl)-benzamide

HRID 1695959

反応式

HRID 1695959 の反応式
C(OC([NH:8][NH:9][C:10]1[CH:15]=[CH:14][C:13]([C:16](=[O:29])[NH:17][CH:18]2[CH2:23][C:22]([CH3:25])([CH3:24])[N:21]([CH3:26])[C:20]([CH3:28])([CH3:27])[CH2:19]2)=[CH:12][CH:11]=1)=O)(C)(C)C>Cl.O1CCOCC1>[NH:9]([C:10]1[CH:15]=[CH:14][C:13]([C:16]([NH:17][CH:18]2[CH2:19][C:20]([CH3:27])([CH3:28])[N:21]([CH3:26])[C:22]([CH3:25])([CH3:24])[CH2:23]2)=[O:29])=[CH:12][CH:11]=1)[NH2:8]

参加物

4

反応物 1

HCID 59515583N'-[4-(1,2,2,6,6-Pentamethyl-piperidin-4-ylcarbamoyl)-phenyl]-hydrazinecarboxylic acid tert-butyl ester

生成物 1

HCID 595155764-Hydrazino-N-(1,2,2,6,6-pentamethyl-piperidin-4-yl)-benzamide

試薬・触媒・溶媒 2

HCID 313Hydrochloric Acid溶媒HCID 312751,4-Dioxane溶媒

実験手順

N′-[4-(1,2,2,6,6-Pentamethyl-piperidin-4-ylcarbamoyl)-phenyl]-hydrazinecarboxylic acid tert-butyl ester was dissolved in 4M HCl in dioxane (30 ml) and left to stir for 1-2 hrs. The solution went quickly from a deep orange colour to a bright orange colour. After 1 hr reaction time, the solvent was removed under vacuum to reveal an orange oil that under a vacuum for several minutes crystallized out to give orange crystals in a sticky orange oil. Yield: 4.68 g, 87%.

後処理

  1. waitleft
  2. customAfter 1 hr reaction time
  3. customthe solvent was removed under vacuum
  4. customfor several minutes
  5. customcrystallized out
  6. customto give orange crystals in a sticky orange oil

出典と根拠

ORDレコード
ord-5b77d78ce39a4fd09e6898eed2cf261a
出典データセット
uspto-grants-2012_04
特許番号
US08163757B2

関連ノート

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