Lawesson's reagent → (2S,4R)-4-Benzenesulfonyl-1-(3-oxo-thiobutyryl)-pyrrolidine-2-carboxylic Acid Methyl Ester
反応式
[CH3:1][O:2][C:3]([C@@H:5]1[CH2:9][C@@H:8]([S:10]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)(=[O:12])=[O:11])[CH2:7][N:6]1[C:19](=O)[CH2:20][C:21](=[O:23])[CH3:22])=[O:4].COC1C=CC(P2(SP(C3C=CC(OC)=CC=3)(=S)S2)=[S:34])=CC=1>>[CH3:1][O:2][C:3]([C@@H:5]1[CH2:9][C@@H:8]([S:10]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)(=[O:12])=[O:11])[CH2:7][N:6]1[C:19](=[S:34])[CH2:20][C:21](=[O:23])[CH3:22])=[O:4]参加物
3
実験手順
In analogy to the procedure described in example 192 g, (2S,4R)-4-benzenesulfonyl-1-(3-oxo-butyryl)-pyrrolidine-2-carboxylic acid methyl ester was reacted with Lawesson's reagent to give the title compound as red oil.
出典と根拠
- ORDレコード
- ord-a61356f57fb147b0a5f990f1dfb1e126
- 出典データセット
- uspto-grants-2012_04