Methyl tricyclo(3.3.1.13,7)dec-1-yl ketone → 3-Hydroxy-alpha-isopropyl-alpha-methyl-1-adamantanemethanol

HRID 1699150ノート

反応式

HRID 1699150 の反応式
[C:1]([C:4]12[CH2:13][CH:8]3[CH2:9][CH:10]([CH2:12][C:6]([OH:14])([CH2:7]3)[CH2:5]1)[CH2:11]2)(=[O:3])[CH3:2].[C:15]([C:18]12CC3CC(CC(C3)C1)C2)(=O)[CH3:16]>>[OH:14][C:6]12[CH2:12][CH:10]3[CH2:9][CH:8]([CH2:13][C:4]([C:1]([CH:15]([CH3:18])[CH3:16])([CH3:2])[OH:3])([CH2:11]3)[CH2:5]1)[CH2:7]2

参加物

3

反応物 2

HCID 123126Methyl tricyclo(3.3.1.13,7)dec-1-yl ketoneHCID 5918961-Acetyl-3-hydroxyadamantane

生成物 1

HCID 120106413-Hydroxy-alpha-isopropyl-alpha-methyl-1-adamantanemethanol収率 48%

実験手順

The procedure of Example 1 was repeated, except that 1.0 mol of 1-acetyl-3-adamantanol obtained according to the process of Reference Example 2 was employed instead of 1-acetyladamantane, to give 3-hydroxy-α-isopropyl-α-methyl-1-adamantanemethanol in yield of 48%.

後処理

  1. customobtained

出典と根拠

ORDレコード
ord-2384d4281c694082a8f0f32f644ed014
出典データセット
uspto-grants-2002_02
特許番号
US06344590B1

反応ノート

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