化工社化工社 化学情報印刷レポート · 研究参考用
1-Bromo-2-methylpropane → 6-(3-fluoro-4-methoxyphenyl)-2-isobutyl-5-(4-methoxyphenyl)-2H-pyridazin-3-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-Bromo-2-methylpropane | HCID 6555 | — |
| 反応物 | 6-(3-fluoro-4-methoxyphenyl)-5-(4-methoxyphenyl)-2H-pyridazin-3-one | HCID 18369367 | — |
| 生成物 | 6-(3-fluoro-4-methoxyphenyl)-2-isobutyl-5-(4-methoxyphenyl)-2H-pyridazin-3-one | HCID 17797527 | 91.3% |
反応手順
Using 6-(3-fluoro-4-methoxyphenyl)-5-(4-methoxyphenyl)-2H-pyridazin-3-one and isobutyl bromide as starting materials, the procedures of Example 146 were repeated likewise, whereby the title compound was obtained in a yield of 91.3%.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06348468B1 |
| 出典データセット | uspto-grants-2002_02 |
| ORD ID | ord-d9fe8f96fe4d47c6b5dd08ab468143ba |
| 出典メモ | uspto-grants-2002_02 |