化工社化工社 化学情報印刷レポート · 研究参考用
(Chloromethyl)cyclopropane → 2-cyclopropylmethyl-6-(3-fluoro-4-methoxyphenyl)-5-(4-methoxyphenyl)-2H-pyridazin-3-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | (Chloromethyl)cyclopropane | HCID 80013 | — |
| 反応物 | 6-(3-fluoro-4-methoxyphenyl)-5-(4-methoxyphenyl)-2H-pyridazin-3-one | HCID 18369367 | — |
| 生成物 | 2-cyclopropylmethyl-6-(3-fluoro-4-methoxyphenyl)-5-(4-methoxyphenyl)-2H-pyridazin-3-one | HCID 18369353 | 93% |
反応手順
Using 6-(3-fluoro-4-methoxyphenyl)-5-(4-methoxyphenyl)-2H-pyridazin-3-one and (chloromethyl)cyclopropane as starting materials, the procedures of Example 146 were repeated likewise, whereby the title compound was obtained in a yield of 93.0%.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06348468B1 |
| 出典データセット | uspto-grants-2002_02 |
| ORD ID | ord-9e8e60cd6cff43d6aed7715f917acb91 |
| 出典メモ | uspto-grants-2002_02 |