関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | 4-Methylmorpholine | HCID 7972 | — |
| 反応物 | Phosphorodichloridic acid, hexyl ester | HCID 6422909 | — |
| 反応物 | HCID 178520956 | HCID 178520956 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | 1,4-Cyclohexanedimethanol | HCID 7735 | — |
反応手順
Under an argon stream, 10 g of trans-1,4-cyclohexane dimethanol (CHDM), 15.25 mL (14.03 g) of N-methyl morpholine (NMM), and 50 mL of methylene chloride were transferred into a 250 mL flash equipped with a funnel. The solution in the flask was cooled down to −40° C. with stirring. A solution of 15.19 g of hexyl phosphoro-dichloridate (HOP) in 20 mL of methylene chloride was added through the funnel, and an additional 10 mL of methylene chloride was used to flush through the funnel. The mixture was then brought up to room temperature gradually and kept stirring for four hours.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US06350464B1 |
|---|
| 出典データセット | uspto-grants-2002_02 |
|---|
| ORD ID | ord-105bc247bb14445c97bf8b2a178c77bf |
|---|
| 出典メモ | uspto-grants-2002_02 |
|---|
