Ammonium Acetate → 1-Amino-5-(2,3-dichlorophenyl)cyclohexen-3-one
反応式
[Cl:1][C:2]1[C:7]([Cl:8])=[CH:6][CH:5]=[CH:4][C:3]=1[CH:9]1[CH2:14][C:13](=O)[CH2:12][C:11](=[O:16])[CH2:10]1.C([O-])(=O)C.[NH4+:21]>C(O)C>[NH2:21][C:13]1[CH2:14][CH:9]([C:3]2[CH:4]=[CH:5][CH:6]=[C:7]([Cl:8])[C:2]=2[Cl:1])[CH2:10][C:11](=[O:16])[CH:12]=1参加物
4
実験手順
A mixture of 5-(2,3-dichlorophenyl)cyclohexane-1,3-dione (1.8 g) and ammonium acetate (1.7 g) in ethanol (20 ml) was refluxed for 14 hours, and the reaction solution was concentrated under reduced pressure. To the residue was added water (20 ml), and the resulting crystals were filtered. The crystals were washed with water and toluene, and dried to give 1-amino-5-(2,3-dichlorophenyl)cyclohexen-3-one (1.6 g) as pale yellow crystals.
後処理
- temperaturewas refluxed for 14 hours
- concentrationthe reaction solution was concentrated under reduced pressure
- additionTo the residue was added water (20 ml)
- filtrationthe resulting crystals were filtered
- washThe crystals were washed with water and toluene
- customdried
出典と根拠
- ORDレコード
- ord-75975a1469fb4bb790a33048dc41b484
- 出典データセット
- uspto-grants-2002_02
- 特許番号
- US06350749B1
反応ノート
読み込み中…