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4,5-Dichloro-2-methylaniline → 5-Chloro-2-methylaniline
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4,5-Dichloro-2-methylaniline | HCID 343796 | — |
| 溶媒 | Hydrochloric Acid | HCID 313 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 5-Chloro-2-methylaniline | HCID 7260 | 82% |
反応手順
Following the general procedure I, 0.25 mol of 4,5-dichloro-2-methylaniline in 200 ml of water and 60 ml of concentrated hydrochloric acid are hydrogenated in the presence of the catalyst from Example 1 at 220° C. over the course of 30 minutes under a hydrogen pressure of 100 atmospheres gauge. 5-Chloro-2-methylaniline is obtained in a yield of 82% and a purity of 99%.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04193937 |
| 出典データセット | uspto-grants-1980_03 |
| ORD ID | ord-8037112fe81848e297759b0be669a25f |
| 出典メモ | uspto-grants-1980_03 |