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Iodoacetamide → 2-((3-Nitrobenzoyl)imino)-5-nitro-3(2H)-thiazoleacetamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Iodoacetamide | HCID 3727 | — |
| 反応物 | Sodium hydride | HCID 24758 | — |
| 反応物 | 3-nitro-N-(5-nitro-1,3-thiazol-2-yl)benzamide | HCID 298930 | — |
| 溶媒 | Dimethylformamide | HCID 6228 | — |
| 生成物 | 2-((3-Nitrobenzoyl)imino)-5-nitro-3(2H)-thiazoleacetamide | HCID 3061827 | — |
反応手順
By following the procedure of Example 5, but using a dispersion of sodium hydride (2.1 g 60% w/w) in mineral oil, 3-nitro-N-(5-nitro-2-thiazolyl)benzamide (11.8 g), N,N-dimethylformamide (100 ml) and 2-iodoacetamide (11.1 g), there was obtained 2-[(3-nitrobenzoyl)imino]-5-nitro-4-thiazoline-3-acetamide, m.pt 251°-252°, after recrystallization from pyridine.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04379156 |
| 出典データセット | uspto-grants-1983_04 |
| ORD ID | ord-2349b54282b249599bf09d1921f4e09b |
| 出典メモ | uspto-grants-1983_04 |