Cyclopropanemethanamine → HCID 13647243、化合物
反応式
[CH:1]1([CH2:4][NH2:5])[CH2:3][CH2:2]1.[CH2:6]([O:8][C:9](=[O:19])[CH2:10][CH:11]=[CH:12][CH2:13][C:14](OCC)=[O:15])[CH3:7]>>[CH:1]1([CH2:4][N:5]2[C:14](=[O:15])[CH2:13][CH2:12][CH:11]2[CH2:10][C:9]([O:8][CH2:6][CH3:7])=[O:19])[CH2:3][CH2:2]1参加物
3
反応条件
- 温度
- 165 °C
実験手順
78 g of cyclopropylmethylamine (1.1 mole) and 220 g of 3-hexenedioic acid diethyl ester are introduced into a liter autoclave. The mixture is heated to 165° C. and then kept at that temperature for 8 hours. After cooling, the product is distilled under vacuum, first eliminating the alcohol, then obtaining 155 g of a compound which distils at 157°-160° C. under 3 mm of Hg.
後処理
- temperatureAfter cooling
- distillationthe product is distilled under vacuum
出典と根拠
- ORDレコード
- ord-265611e3ddf74372ad97174a7d41eb4c
- 出典データセット
- uspto-grants-1983_04
- 特許番号
- US04379161
反応ノート
読み込み中…