Acetic Anhydride → HCID 15580722、化合物
反応式
[NH2:1][C:2]1[CH2:6][CH:5]([CH3:7])[N:4]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[N:3]=1.[C:14](OC(=O)C)(=[O:16])[CH3:15]>CN(C)C1C=CN=CC=1.ClCCl>[CH3:7][CH:5]1[N:4]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[N:3]=[C:2]([NH:1][C:14](=[O:16])[CH3:15])[CH2:6]1参加物
5
実験手順
A mixture of 2.0 g. of 3-amino-5-methyl-1-phenyl-2-pyrazoline (prepared in Example 5), 5.0 ml. of acetic anhydride and 100 mg. of 4-dimethylaminopyridine is allowed to stand at room temperature for 3 hours. The mixture is filtered to give a white solid. The solid is dissolved in dichloromethane and is columnized and recrystallized as for Example 14 (B) to give 0.90 g. of the desired product as colorless plates, m.p. 144.5-146.5° C.
後処理
- additionA mixture of 2.0 g
- filtrationThe mixture is filtered
- customto give a white solid
- customto give 0.90 g
出典と根拠
- ORDレコード
- ord-9ca8831bee114921bbe92dbfff95a0bd
- 出典データセット
- uspto-grants-1982_09
- 特許番号
- US04348527
反応ノート
読み込み中…