Benzene → [(2-Isocyanatoethyl)thio]benzene
反応式
C1(C[CH2:8][C:9](O)=[S:10])C=CC=CC=1.C1(P(N=[N+]=[N-])(C2C=CC=CC=2)=[O:19])C=CC=CC=1.C([N:31]([CH2:34]C)CC)C.[CH:36]1[CH:41]=[CH:40][CH:39]=[CH:38][CH:37]=1>>[C:36]1([S:10][CH2:9][CH2:8][N:31]=[C:34]=[O:19])[CH:41]=[CH:40][CH:39]=[CH:38][CH:37]=1参加物
5
実験手順
The reaction of 3-phenylthiopropionic acid and diphenylphosphoryl azide in a solution of triethyl amine and benzene provided a solution comprising 2-phenylthioethyl isocyanate (I.R.: 2260 cm-1), which was reacted with 5-fluorouracil to provide 1-[N-(2-phenylthioethyl)carbamoyl]-5-fluorouracil substantially in the similar method to that of Example 10.
出典と根拠
- ORDレコード
- ord-6c630ab939424b77a18c7d2b822bcb98
- 出典データセット
- uspto-grants-1982_09
- 特許番号
- US04349552
反応ノート
読み込み中…