Methane → Carbamimidothioic acid(3-methyl-2-quinoxalinyl)ester, hydrochloride

関与物質

反応手順

2-Chloro-3-methylquinoxaline (10.72 g., 0.06 mole) was dissolved in 150 ml. of acetone, treated with Norit and filtered. The filtrate was added to 4.56 g. (0.06 mole) of thiourea in 150 ml. acetone. The solution was stirred at reflux under nitrogen for 2 hours. The precipitate which began to form after 5 minutes, was filtered while the reaction mixture was hot. The solid was collected, washed with hot acetone and dried to give 11.85 g. of a pink solid, m.p. 156°-157° C.

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