ホームMCPワークベンチSkills
ホームワークベンチ通知マイページ
llms.txt · MCPガイドプライバシーポリシー · 利用規約 · サポートv1.8.0
  1. ホーム
  2. /反応

Methane → N,N'-Bis(2-propenyl)carbamimidothioic acid(3-methyl-2-quinoxalinyl)ester, hydrochloride

HRID 1702840
ノート
印刷プレビュー

反応式

HRID 1702840 の反応式
[Cl:1][C:2]1[C:11]([CH3:12])=[N:10][C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[N:3]=1.CO.C.[CH2:16]([NH:19][C:20]([NH:22][CH2:23][CH:24]=[CH2:25])=[S:21])[CH:17]=[CH2:18]>CC(C)=O>[ClH:1].[CH3:12][C:11]1[C:2]([S:21][C:20](=[N:19][CH2:16][CH:17]=[CH2:18])[NH:22][CH2:23][CH:24]=[CH2:25])=[N:3][C:4]2[C:9]([N:10]=1)=[CH:8][CH:7]=[CH:6][CH:5]=2
参加物実験手順後処理出典と根拠反応ノート

参加物

6

反応物 4

HCID 297MethaneHCID 887Methanol2 回HCID 2362762-Chloro-3-methylquinoxalineHCID 3034186Thiourea, N,N'-di-2-propen-1-yl-

生成物 1

HCID 131712831N,N'-Bis(2-propenyl)carbamimidothioic acid(3-methyl-2-quinoxalinyl)ester, hydrochloride収率 61.5%

試薬・触媒・溶媒 1

HCID 180
Acetone
溶媒

実験手順

2-Chloro-3-methylquinoxaline (3.56 g., 0.02 mole) was dissolved in 50 ml. of methanol, treated with Norit and filtered. The filtrate was added to 3.125 g. (0.02 mole) of 1,3-diallylthiourea in 50 ml. of methanol. The mixture was stirred at room temperature for 31/2 hours, then freed of solvent. Acetone was added to the residue and the solution again freed of solvent. The residue was triturated with ether and with acetone, filtered, washed and dried to give 4.12 g. (61.5% yield), m.p. 90°-93° C.

後処理

  1. filtrationfiltered
  2. additionThe filtrate was added to 3.125 g
  3. customThe residue was triturated with ether and with acetone
  4. filtrationfiltered
  5. washwashed
  6. customdried
  7. customto give 4.12 g

出典と根拠

ORDレコード
ord-d4d809f5afe249688c60105838fe0964
出典データセット
uspto-grants-1982_09
DOI
10.6084/m9.figshare.5104873.v1
特許番号
US04349674

反応ノート

読み込み中…

このページの内容参加物実験手順後処理出典と根拠反応ノート