HCID 22761198、化合物 → HCID 21330037、化合物
反応式
[C:1]1([N:7]2[CH2:11][CH2:10][CH:9]([NH:12][C:13](=[O:23])[C:14]3[CH:19]=[CH:18][C:17]([N+:20]([O-])=O)=[CH:16][CH:15]=3)[CH2:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[H][H]>C(O)C>[C:1]1([N:7]2[CH2:11][CH2:10][CH:9]([NH:12][C:13](=[O:23])[C:14]3[CH:15]=[CH:16][C:17]([NH2:20])=[CH:18][CH:19]=3)[CH2:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1参加物
4
実験手順
A suspension of 10 g. of 1-phenyl-3-(4-nitrobenzamido)pyrrolidine in 250 ml. of 95% ethanol containing 5% palladium on charcoal was shaken in a Paar hydrogenator in three atmospheres of hydrogen at room temperature. The reduction mixture was filtered and the filtrate concentrated to give 3.8 g. of crystalline product which melted at 213-216° C.
後処理
- additionA suspension of 10 g
- filtrationThe reduction mixture was filtered
- concentrationthe filtrate concentrated
- customto give 3.8 g
出典と根拠
- ORDレコード
- ord-acf2d78f40af45738bf479f9891415c8
- 出典データセット
- uspto-grants-1978_11
- 特許番号
- USRE029828
反応ノート
読み込み中…