Thiourea, N,N'-di-2-propen-1-yl- → 3-Allyl-2-allylimino-4-(4-chloro-3-sulfamoylphenyl)-1,3-thiazolidine-4-ol-hydrochloride
反応式
[Cl:1][CH2:2][C:3]([C:5]1[CH:10]=[CH:9][C:8]([Cl:11])=[C:7]([S:12](=[O:15])(=[O:14])[NH2:13])[CH:6]=1)=[O:4].[CH2:16]([NH:19][C:20]([NH:22][CH2:23][CH:24]=[CH2:25])=[S:21])[CH:17]=[CH2:18]>>[ClH:1].[CH2:23]([N:22]1[C:3]([C:5]2[CH:10]=[CH:9][C:8]([Cl:11])=[C:7]([S:12](=[O:15])(=[O:14])[NH2:13])[CH:6]=2)([OH:4])[CH2:2][S:21][C:20]1=[N:19][CH2:16][CH:17]=[CH2:18])[CH:24]=[CH2:25]参加物
3
実験手順
5.2 g of 2,4'-dichloro-3'-sulfamoylacetophenone and 2.5 g of 1,3-diallyl-thiourea were reacted according to the prescription given in Example 12, the end product was precipitated with diisopropyl ether and the oil obtained was crystallized with diethyl ether/ethyl acetate (1:1). Colorless solid body: melting point: 158° C. (decomposition).
後処理
- customthe end product was precipitated with diisopropyl ether
- customthe oil obtained
- customwas crystallized with diethyl ether/ethyl acetate (1:1)