N-Cyclohexyl-N′-(2-pyridinylmethyl)thiourea → HCID 22760591、化合物
反応式
[Br:1][CH2:2][C:3]([C:5]1[CH:10]=[CH:9][C:8]([Cl:11])=[C:7]([S:12](=[O:15])(=[O:14])[NH2:13])[CH:6]=1)=[O:4].[CH:16]1([NH:22][C:23]([NH:25][CH2:26][C:27]2[CH:32]=[CH:31][CH:30]=[CH:29][N:28]=2)=[S:24])[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17]1>>[BrH:1].[Cl:11][C:8]1[CH:9]=[CH:10][C:5]([C:3]2([OH:4])[CH2:2][S:24][C:23](=[N:25][CH2:26][C:27]3[CH:32]=[CH:31][CH:30]=[CH:29][N:28]=3)[N:22]2[CH:16]2[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17]2)=[CH:6][C:7]=1[S:12](=[O:15])(=[O:14])[NH2:13]参加物
3
実験手順
4.7 g of 2-bromo-4'-chloro-3'-sulfamoylacetophenone and 3.75 g of 1-cyclohexyl-3-(2-pyridylmethyl)-thiourea were reacted according to the prescription given in Example 23 and the crystals were filtered off. Colorless solid body, melting point: 249° C. (decomposition).
後処理
- filtrationthe crystals were filtered off
出典と根拠
- ORDレコード
- ord-2c71632938044e81ad83dfac09a64a4e
- 出典データセット
- uspto-grants-1978_11
- DOI